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BALR/PF-NI Summer Studentship: Alexander Reid

As a second-year medical student, I never imagined I would have the chance delve into research Yet, here I am, reflecting on an incredible summer studentship with the British Association for Lung Research (BALR).

 

From day one, I was immersed in research, guided by my supervisor Dr Schock, whose passion for research was truly infectious. Each day was a blend of learning and hands-on experience. I was able to conduct novel and useful research, and I saw firsthand how our work could lead to new understanding and perspective on pulmonary fibrosis.

 

My project investigated the epithelial protein HE4 (human epididymis protein 4), which is increased in secretions of airway epithelial cells, particularly in fibrotic conditions. Little is known about its function, but pro-fibrotic effects have been reported. However, supernatant of airway epithelial cells without HE4 appears to stimulate collagen production in culture. I found that HE4 deficient epithelial cells secrete more pro-fibrotic cytokines, suggesting that HE4 might have a regulatory role in airway diseases.

 

One of the most rewarding aspects was being invited to present my research at the Irish Thoracic Society annual meeting. It showed me that the research the BALR enabled me to conduct was interesting to experts in the field, which gave me a great sense of achievement. I am looking forward to presenting it this November.

 

I also learned a massive array of new skills in the lab, from Western Blotting to scRNA-Seq and cell culture. I also developed the lesser thought of research skills: data analysis, record keeping and data presentation. All of these skills are invaluable, and it was a great experience to learn them so early in my career pathway.

 

This studentship wasn't just about the technical skills and knowledge gained; it was about growing as a future clinician scientist. I’ve learned the importance of collaboration, resilience, and the relentless pursuit of knowledge. I am profoundly thankful to BALR for this opportunity and for the chance to be part of such meaningful work.

 

Here’s to many more summers of learning, discovery, and making a difference.

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